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Table 5 Factors associated with PRBC transfusion requirement during the first 24 h

From: Incidence rate and topography of intra-pelvic arterial lesions associated with high-energy blunt pelvic ring injuries: a retrospective cohort study

  Univariate analysis Multivariable analysisa
Variables OR 95% CI p-value OR 95% CI p-value
IPAL (ref. no arterial lesion) 5.81 1.73–19.49 0.004 4.53 1.23–16.66 0.023
Hemodynamic instability (ref. none) 28.50 8.85–91.74 < 0.001
Female gender (ref. male) 0.69 0.33–1.45 0.331 0.81 0.37–1.79 0.610
Age in categories (ref. 16–39 years)    0.696    0.763
 40–49 0.53 0.18–1.55 0.247 0.53 0.17–1.68 0.284
 50–69 0.93 0.39–2.23 0.868 0.89 0.35–2.26 0.811
  ≥ 70 years 1.00 0.31–3.21 0.999 0.87 0.24–3.07 0.825
ISS, continuous 1.17 1.11–1.24 < 0.001
ISS ≥25 (ref. < 25) 14.63 5.87–36.47 < 0.001
AO/OTA classification (ref. A)    0.077
 B 1.13 0.43–2.92 0.808    
 C 3.38 0.99–11.46 0.051    
Young and Burgess classification (ref. NC)    0.367    0.688
 LC 1.04 0.39–2.76 0.937 0.94 0.34–2.58 0.907
 APC 1.86 0.50–6.94 0.356 1.31 0.30–5.77 0.723
 VS & CM 2.39 0.67–8.51 0.179 1.87 0.48–7.24 0.365
  1. a Hosmer-Lemeshow test, p = 0.589. The variance inflation factors (VIF) are all below 1.2, suggesting no collinearity
  2. After adjustment for sex and age, the presence of an IPAL was significantly associated with greater odds of PRBC transfusion independently of the types of PRI. Neither ISS nor hemodynamic instability was introduced in the regression model as both these factors were on the causal pathway from IPAL to transfusion
  3. OR: odds ratio; 95% CI: 95% confidence interval; IPAL: intra-pelvic arterial lesion; ISS: Injury Severity Score; NC: not classifiable; LC: lateral compression; APC: anteroposterior compression; VS: vertical shear; CM: combined mechanism